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Cumulative exposure to a neighborhood characterized as socioeconomically disadvantaged increases the odds of functional limitations by 20 percent and death by 40 percent over time, even after accounting for an individual’s own economic and social status, Dr. Philippa Clarke said in an interview on The interview focused on Dr. Clarke and colleagues’ recently published study “Cumulative Exposure to Neighborhood Context Consequences for Health Transitions Over the Adult Life Course,” which used ACL data to examine the relationship between respondents residential neighborhoods over time and their health over time.